The lab has opened in March 2018
We are excited to build a state-of-the-art environment for the study of host-microbiome interactions and epithelial cell biology. We are currently looking for highly talented and motivated scientists at all…
Understanding modern human disease is only possible from the perspective of the metagenome, the entirety of all microbial genomes associated with the human body. We study the interface between the host and its microbiome in the gastrointestinal tract, with a particular focus on microbiome-derived metabolites. We are a newly opened lab at the Microbiology Department, University of Pennsylvania.
New review in Nature Reviews Immunology
Throughout the past century, we have seen the emergence of a large number of multifactorial diseases, including inflammatory, autoimmune, metabolic, neoplastic and neurodegenerative diseases, many of which have been recently…
New paper on epithelial-microbiota interactions in Cell
The intestinal microbiota undergoes diurnal compositional and functional oscillations that affect metabolic homeostasis, but the mechanisms by which the rhythmic microbiota influences host circadian activity remain elusive. Using integrated multi-omics…