Welcome to the LevyLab

We study the host-
microbiome interface

We use immunogenomics
and metabolomics

Welcome to the LevyLab

Understanding modern human disease is only possible from the perspective of the metabolome, the entirety of all small molecules associated with the human body. We study the metabolome at interface between the host and its microbiome in the gastrointestinal tract. We are a located at the Microbiology Department, University of Pennsylvania.

The intestinal epithelium

We study new epithelial cell function in host-microbiome interactions


We investigate the role of microbiota-derived metabolites in host health and disease

Innate immunity

We explore new features of the intestinal innate immune response to the microbiota

New paper on Long COVID published in Cell

Post-acute sequelae of COVID-19 (PASC, “Long COVID”) pose a significant global health challenge. The pathophysiology is unknown, and no effective treatments have been found to date. Several hypotheses have been…

Maayan Levy receives BWF PATH Award

Congratulations to Maayan for being named a Burroughs Wellcome Fund (BWF) Investigators in the Pathogenesis of Infectious Disease (PATH) award! The BWF PATH grants are awarded to support innovative ideas…

New paper on psychological stress in IBD published in Cell

Mental health profoundly impacts inflammatory responses in the body. This is particularly apparent in inflammatory bowel disease (IBD), in which psychological stress is associated with exacerbated disease flares. Here, we…

We are recruiting highly talented and motivated individuals to join our lab!