Nuclear Retention of mRNA in Mammalian Tissues mRNA is thought to predominantly reside in the cytoplasm, where it is translated and eventually degraded. Although nuclear retention of mRNA has a…
Metagenomic cross-talk: the regulatory interplay between immunogenomics and the microbiome The human microbiome, often referred to as the ‘second genome’, encompasses up to 100-fold more genes than the host genome.…
Chronobiomics: The Biological Clock as a New Principle in Host-Microbial Interactions Visit full artice page: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005113
A day in the life of the meta-organism: diurnal rhythms of the intestinal microbiome and its host Life on Earth is dictated by circadian changes in the environment, caused by…
Taming the inflammasome The NLRP3 inflammasome is involved in the molecular etiology of multiple autoinflammatory diseases. Two studies identify inhibitors of NLRP3 activation and might pave the way for new…